KANAMYCIN PHOSPHOTRANSFERASE I: MECHANISM OF CROSS RESISTANCE BETWEEN KANAMYCIN AND LIVIDOMYCIN
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چکیده
منابع مشابه
Cross-resistance Relationships between Paromomycin (aminosidine), Lividomycin, Kanamycin, and Capreomycin Resistances of Mycobacterium Tuberculosis
Introduction Paromomycin1•`4) and aminosidineo are aminoglucoside antibiotics recently discovered. Identity of paromomycin and aminosidine has been reportedo. Knowledge of cross-resistance-relationships in respect to this antibiotic is very scanty. ARCAMONE et al. 5) stated that a neomycin-resistant strain of Staphylococcus aureus was resistant to paromomycin. The present study was carried out ...
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An A1400G mutation of the rrs gene was identified in Mycobacterium tuberculosis (MTB) strain ATCC 35827 and in 13 MTB clinical isolates resistant to amikacin-kanamycin (MICs, >128 microg/ml). High-level cross-resistance may result from such a mutation since MTB has a single copy of the rrs gene. Another mechanism(s) may account for high-level amikacin-kanamycin resistance in two mutants and low...
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The recent developments of transcription activator-like effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein-9 nuclease (Cas9) have expanded plant breeding technology. One technical issue related to the current genome editing process is residual transgenes for TALEN and CRISPR/Cas9 left in plant genomes after the editing pro...
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A strain of Proteus vulgaris isolated from the urinary tract of a patient with postoperative pyelonephritis and resistant to sulfonamide, streptomycin, tetracycline, and kanamycin (KM) was found to transfer only KM resistance by cell-to-cell conjugation. The genetic determinant controlling the transferable KM resistance was considered to be an R factor and was designated R (KM). Successive tran...
متن کاملCloning of the kanamycin resistance gene from a kanamycin-producing Streptomyces species.
A kanamycin-producing strain, Streptomyces kanamyceticus ISP5500, is resistant to kanamycin. A kanamycin resistance determinant was cloned from S. kanamyceticus into Streptomyces lividans 1326, using the plasmid vector pIJ702. The resulting plasmid, pMCP5, could also transform Streptomyces lavendulae S985 and Streptomyces parvulus 2283 to kanamycin resistance. Transformants carrying pMCP5 were ...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1973
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.26.407